From airports to the hotel:
If you are flying in to either O'Hare or Midway airport, there are various options for getting to the hotel:

1. Taxi: from O'Hare to downtown, cost is approx. $40; from Midway to downtown, approx. $35. Travel time from either is about 45 minutes to an hour, depending on traffic. Make sure to give the taxi driver the hotel's address, 75 East Wacker Drive, since there is more than one Club Quarters hotel location in Chicago.

2. Subway:
(a)From O'Hare airport, the CTA Blue Line runs to downtown Chicago, leaving from the lower level of the airport, below Terminal 3. If Chicago is your entry point to the U.S., you will arrive at the International Terminal (Terminal 5); in that case, once you clear customs, take the free Airport Transit System (ATS) tram to Terminal 3, follow the crowd to the Terminal, and then go all the way downstairs and follow signs to the subway (CTA). Take the Blue Line train to the Clark & Lake Station, located at 124 West Lake St. From there it is about a seven-block walk (see map) to the Club Quarters Hotel, 75 East Wacker Drive. CTA subway map is here. Subway fare to downtown is about $2.00.
(b)From Midway airport, take the Orange Line train to the State & Lake Station, located at 200 N. State St, about 4 blocks from the hotel at 75 E. Wacker (see map). Fare is $2.00.

3. Car rental: All the major car rental agencies operate from both airports. Note that parking in/near the hotel is expensive.

Driving from out of town to the hotel:
If you're driving, you're probably coming from the south. If so, the standard route is to get onto I-90/94 north (Dan Ryan Expwy), then exit onto Congress Parkway/290 going east (toward the loop). Turn left (north) onto State St., then right onto Wacker. See map of downtown Chicago. Note that there is currently extensive construction on the Dan Ryan, so you may want to use Lake Shore Drive to make your way north instead.

Driving from out of town to U. Chicago:
From the west, take I-88 East to 290 East to 90/94 South (Dan Ryan), and exit at 55th St; after coming up the ramp, turn left at the light onto 55th St. After about 8 blocks, 55th becomes Garfield Blvd; cross Martin Luther King Drive and bear right to go through Washington Park. You will soon come to a fork, where you bear left, then take the next right which gets you back onto East 55th Street (still heading east). You will first pass Cottage Grove; at the next intersection, turn right onto Ellis Ave., then an immediate left into the parking garage at the corner of 55th and Ellis. Once parked, walk 2.5 blocks south along Ellis to the KPTC, which is on Ellis between 57th and 58th.
Alternate route: the Dan Ryan is under construction, in which case you may want to take 290 East all the way to its end in downtown Chicago, turn right onto Columbus, and then merge onto Lake Shore Drive South. Take the exit at 53rd St., take an immediate left and head south to 55th St., where you turn right (west), and after a number of blocks turn left onto Ellis and immediate left into the parking garage and then see above.
Third alternative is to take 290 East to 90/94 south, then I-55 north to Lake Shore Drive south, and then follow directions above.

From the south (Urbana): you are probably coming up I-57; then take 94 (Dan Ryan) to 55th St. exit, turn right at top of ramp onto 55th St., and follow directions above. If Dan Ryan construction is a nightmare, then you could try to exit from I-94 around 95th St., go east on 95th, turn left (north) onto Stony Island. Take Stony Island north, turn left onto 59th St., then right onto Ellis Avenue and go 4 blocks north to the parking garage at Ellis and 55th St. Then follow walking directions above.

From the east (Michigan): coming toward Chicago, follow signs to the I-90 toll road (Chicago Skyway). Due to the construction on the Dan Ryan (I-94), I suggest exiting the Skyway at Stony Island Ave (heading north), and then follow the directions above.

Public transport from western suburbs to U. Chicago:
Here is info. from Steve Kent:
Metra provides train service to downtown Chicago: Metra.

The CTA runs express buses (192) between the Union and Northwest train stations and campus during the morning and evening rush hours. For those without CTA fare cards, the bus fare is $2 (exact change - bills accepted) each way: look here.

The door-to-door travel time from Batavia area (depending on which train you take) is of order 2 hrs.

Other options for people commuting from yet other directions: here.

Transportation between hotel and U. Chicago:
We will have our own buses running from the hotel to the meeting venue at U. Chicago on Monday, Tuesday, and Wednesday mornings of the meeting; departure time from the hotel will be 8:15 am.

For return travel from campus to the hotel in the evenings, the best option is bus (or walking) to the Metra rail line:
The CTA 170/U. Chicago Midway bus runs from the U. Chicago hospital (the entrance at 860 East 59th St.) to the two nearby Metra rail stations, one at 57th and Lake Park Ave., the other at 59th and Harper Ave. This bus runs from 6:30 to 9:00 am in the morning and from 3:30 to 7 pm in the evening. For exact schedule and route information visit the CTA Web site. Alternatively, the walk from the meeting venue to the 57th St. Metra station is about 20 minutes.

The Metra Line runs from Hyde Park (either the 57th St. or 59th St. stations) to downtown. The last station, at Milennium Park (Michigan Ave. near Randolph, see map, is about 6-7 blocks from the hotel.

You will also notice that the elevated CTA Green Line (``the El") runs from downtown to 63rd St. and Cottage Grove, about 7 blocks south and a couple of blocks west of the meeting venue. In the evening, this is only recommended for the more adventurous. The previous stop, at 55th St., is a bit further away from campus, but there is bus service from there to campus.

Here are maps of the campus, the Hyde Park neighborhood, and beyond.